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Avogadro's number, which is a fundamental constant in chemistry, represents the number of atoms, molecules, or particles in one mole of a substance. This number is crucial for converting between the number of molecules and the amount of substance in moles, which allows chemists to quantify reactions and relationships in chemical equations. The accepted value of Avogadro's number is approximately 6.022 x 10^23, which is used universally in calculations involving moles.

This definition underpins why the choice indicating 6.022 x 10^23 is the correct answer, as it aligns with established scientific standards and empirical data. Understanding Avogadro's number is essential for grasping larger concepts in stoichiometry, molecular weight, and chemical reactions in general, which are central topics in the MCAT and other chemistry-related disciplines.